Encyclopaedia

Explore comprehensive, evidence-informed explanations of key health economics concepts, including their development, application and relationships to other concepts. Published entries are validated through human expert review.

6180 of 1014 concepts

Best-Worst Scaling

A stated preference method in which respondents identify both the most and least preferred items from a set, rather than ranking every item.

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Beta Distribution

A flexible probability distribution bounded between zero and one, commonly used to represent uncertainty in probability parameters.

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Beta Level

The predetermined acceptable probability of failing to detect a true effect, with one minus beta defining a study's statistical power.

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Between-Study Heterogeneity

The genuine variation in true treatment effects across the studies in a meta-analysis, beyond what chance alone would explain.

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Between-Subject Variation

The variability in an outcome measure observed across different individuals in a study, unlike within-subject variation in a single person's repeated measurements.

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Bias-Variance Tradeoff

The tension in statistical modelling between a model's systematic error, or bias, and its sensitivity to the specific sample used to fit it, or variance.

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Big O Notation

An asymptotic notation that expresses an upper bound on how an algorithm?s resource use grows as input size increases, disregarding constant factors and lower-order terms.

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Binary Representation

The encoding of numerical values using the binary number system, where all information is represented as combinations of 0s and 1s.

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Binomial Distribution

A discrete probability distribution describing the number of successes in a fixed number of independent trials with the same success probability each.

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Bisection Method

A numerical root-finding method that repeatedly halves an interval known to contain a root until the required level of accuracy is achieved.

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Block Randomization

A randomisation technique assigning participants to groups in balanced blocks of a set size, keeping numbers roughly equal throughout enrolment.

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Bootstrap Standard Error

An estimate of a parameter's statistical uncertainty, calculated as the standard deviation of its value across many resampled datasets via bootstrapping.

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Bootstrapping

A resampling technique estimating a statistic's sampling distribution by repeatedly drawing random samples, with replacement, from the original observed data.

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Bootstrapping Method

The specific procedure of repeatedly resampling, with replacement, from a dataset to empirically approximate the sampling distribution of a statistic of interest.

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Bottom-Up Costing

A costing method that estimates total cost by measuring detailed resource use at the individual patient level and aggregating those measurements.

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Break-Even Analysis

An analysis identifying the point at which the costs and benefits, or revenues, of an activity are equal.

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Break-Even Point

The level of output or activity at which total revenue equals total cost, so an organisation neither gains nor loses money.

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Breakeven Analysis

An analysis identifying the point at which total costs equal total revenues or benefits, so an activity neither gains nor loses value.

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Brier Score

A measure of probabilistic prediction accuracy, the mean squared difference between predicted probabilities and actual observed binary outcomes, lower being better.

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Budget Impact

The projected change in total spending for a payer or health system resulting from adopting a new treatment or policy.

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