Encyclopaedia

Explore comprehensive, evidence-informed explanations of key health economics concepts, including their development, application and relationships to other concepts. Published entries are validated through human expert review.

Concepts, entries and ontology terms

A concept page is a published entry on the wiki. Some concepts also have a full encyclopaedia article. The Health Economics Ontology (HEO) holds every concept, including dictionary terms without an article, so it is larger than the list of published pages. The knowledge graph shows how concepts relate to each other.

Data Envelopment Analysis

Data envelopment analysis (DEA) is a linear programming method that scores hospitals and other health care units on technical efficiency against peers.

Health PolicyExpert Verified5 related concepts

Data Exclusivity

Data exclusivity is the period after a medicine's first approval in which generic or biosimilar applicants may not rely on the originator's trial data.

Drug CostsExpert Verified5 related concepts

DFLE Calculation

The process of computing disability-free life expectancy using a life table combining age-specific mortality rates with age-specific disability prevalence.

Economic EvaluationExpert Verified3 related concepts

Direct Elicitation

Direct elicitation is the valuation of a health state by asking people to trade it against life years or risk of death, rather than through a value set.

Economic EvaluationExpert Verified5 related concepts

Disability Weight

A disability weight is a value from 0 (full health) to 1 (equivalent to death) rating health loss in a non-fatal state, used to calculate YLDs and DALYs.

Economic EvaluationExpert Verified4 related concepts

Disability-Adjusted Life Year

The disability-adjusted life year (DALY) measures health loss by adding years of life lost to premature death and years lived with disability.

Economic EvaluationExpert Verified7 related concepts

Disease-Free Survival

Disease-free survival (DFS) is the time from randomisation until cancer recurrence or death from any cause, an endpoint of adjuvant trials and models.

Evidence SynthesisExpert Verified6 related concepts

Distribution-Based MID

A distribution-based MID is a minimal important difference estimated from score spread or instrument reliability, such as half a standard deviation.

Economic EvaluationExpert Verified5 related concepts

Disutility

Disutility is the loss of utility caused by a health state, adverse event or treatment, measured from a stated baseline and used to reduce QALYs.

Economic EvaluationExpert Verified4 related concepts

Drug Pricing

Drug pricing is how manufacturers and payers set and negotiate the amount paid for a medicine, under government pricing policies and patent protection.

Drug CostsExpert Verified3 related concepts

ECOG Performance Status

ECOG Performance Status is a clinician-rated six-grade scale of a cancer patient's functioning, grade 5 being death, used for trial eligibility and models.

Evidence SynthesisExpert Verified4 related concepts

Efficiency Index

An efficiency index is one number comparing the resources a hospital or health system uses with its outputs, against peers, national costs or a frontier.

NHS ProductivityExpert Verified3 related concepts

EORTC QLU-C10D

EORTC QLU-C10D is a cancer-specific preference-based measure that scores 13 QLQ-C30 items with national value sets to give utilities for QALYs.

Economic EvaluationExpert Verified6 related concepts

EQ-5D-3L Value Set

EQ-5D-3L value sets are utility weights, elicited from a population's health state valuations, that score all 243 EQ-5D-3L states for QALY calculation.

Economic EvaluationExpert Verified3 related concepts

EQ-5D-5L Value Set

EQ-5D-5L value set is a scoring algorithm, estimated from a general public valuation study, that gives each of the 3,125 EQ-5D-5L states a QALY utility.

Economic EvaluationExpert Verified4 related concepts

EQ-HWB-S

EQ-HWB-S, renamed EQ-HWB-9, is the nine-item short form of the EQ Health and Wellbeing measure, with a UK pilot value set giving utilities for QALYs.

Economic EvaluationExpert Verified7 related concepts

Event-Free Survival

Event-free survival (EFS) is the time, usually from randomisation, to the first prespecified event, such as recurrence or death, in trials and models.

Evidence SynthesisExpert Verified2 related concepts

Expanded Disability Status Scale

Expanded Disability Status Scale (EDSS) is a clinician-rated 0 to 10 scale of multiple sclerosis disability, often used to set health states in MS models.

Evidence SynthesisExpert Verified3 related concepts

External Reference Pricing

A medicine-pricing policy that uses prices for the same or comparable product in other jurisdictions as benchmarks for a domestic price or reimbursement decision.

Drug CostsExpert Verified5 related concepts

FLACC Scale

FLACC Scale is an observer-rated pain score for young or non-verbal children, totalling 0 to 10, used as a trial outcome but unable to give QALYs directly.

Evidence SynthesisExpert Verified4 related concepts