Individual patient data meta-analysis systematically obtains, checks, and jointly synthesises participant-level records from eligible studies to estimate effects and investigate variation across studies or patients.
Evidence Synthesis
Terms for finding, appraising and pooling research evidence, including systematic review and network meta-analysis.
- Topic: Evidence Synthesis
- 38 terms
- Editor reviewed
A systematic review continually updated as new relevant evidence becomes available, rather than conducted once and left static.
A method comparing treatments from separate trials with different populations by reweighting one trial's patient data to match the other trial's reported characteristics.
Meta-analysis statistically combines effect estimates from multiple studies addressing a sufficiently similar question.
An evidence synthesis summarising findings from multiple studies primarily through descriptive text, rather than formal statistical pooling.
Network meta-analysis, or NMA, compares three or more interventions by combining direct evidence from head-to-head studies with indirect evidence connected through common comparators.
A technique testing for inconsistency in a network meta-analysis by separately estimating direct and indirect evidence for one comparison and comparing them.
A meta-analysis combining evidence comparing exactly two treatments, unlike a network meta-analysis synthesising evidence across three or more.