Evidence Synthesis

Terms for finding, appraising and pooling research evidence, including systematic review and network meta-analysis.

  • Topic: Evidence Synthesis
  • 38 terms
  • Editor reviewed

5 terms

I-SquaredI2 Statistic, Higgins I2

A statistic quantifying the percentage of total variation across studies in a meta-analysis attributable to genuine heterogeneity rather than chance.

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InconsistencyDirect-Indirect Discrepancy, Evidence Discordance

Within network meta-analysis, a discrepancy between direct and indirect evidence for the same comparison, indicating the two sources disagree.

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Indirect ComparisonAnchored Comparison, Bucher Method, Indirect Treatment Comparison, ITC

A method estimating the relative effect of two treatments never studied against each other directly, using their separate effects versus a shared comparator.

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Indirect EvidenceIndirect NMA Evidence, Chained Evidence

Within network meta-analysis, evidence comparing two treatments derived through a chain of comparisons via a common comparator, not from direct trials.

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Individual Patient Data Meta-AnalysisIPD Meta-Analysis, IPD-MA, Individual Participant Data Meta-Analysis, Participant-Level Meta-Analysis, Patient-Level Meta-Analysis

Individual patient data meta-analysis systematically obtains, checks, and jointly synthesises participant-level records from eligible studies to estimate effects and investigate variation across studies or patients.

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