Per-Protocol AnalysisPP Analysis, On-Treatment Analysis
An analysis including only trial participants who received and adhered to their assigned treatment as specified, excluding those with major protocol deviations.
Clinical Trials & Real-World Evidence
Terms for clinical trial design and for evidence drawn from routine practice outside trials.
- Topic: Clinical Trials & Real-World Evidence
- 40 terms
- Editor reviewed
PharmacovigilanceDrug Safety Monitoring, Safety Surveillance
The science and activities relating to detecting, assessing, understanding, and preventing adverse effects of a medicine throughout its entire lifecycle.
Placebo EffectPlacebo Response, Expectation Effect
An improvement in a patient's condition resulting from belief in receiving an effective treatment, occurring independently of any direct pharmacological action.
Pragmatic TrialReal-World Trial, Effectiveness Trial
A trial designed to evaluate a treatment under conditions resembling routine clinical practice, using broad eligibility and outcomes relevant to real-world decisions.
Primary EndpointPrimary Outcome, Principal Endpoint
The main outcome measure a trial is specifically designed and statistically powered to assess, the principal basis for judging its success.
Propensity ScorePS, Treatment Probability Score
The estimated probability that an individual would receive a particular treatment given their observed characteristics, used to balance confounders in observational studies.