Efficacy-Effectiveness GapEfficacy-Effectiveness Difference, Trial-to-Practice Gap
The observed difference between a treatment's trial-demonstrated benefit and its actual benefit once used in routine clinical practice.
Clinical Trials & Real-World Evidence
Terms for clinical trial design and for evidence drawn from routine practice outside trials.
- Topic: Clinical Trials & Real-World Evidence
- 40 terms
- Editor reviewed
Electronic Health RecordEHR, Digital Patient Record
A digital, longitudinal record of a person’s health information maintained for care and, where permitted, shared or reused across authorised settings and purposes.
Equivalence TrialEquivalence Study, Therapeutic Equivalence Study
A trial designed to show a new treatment's effect is neither substantially better nor worse than an existing treatment, within a set margin.
External Control ArmRegistry Control Group, Synthetic Control Arm
A comparator group built from data outside the trial itself, such as a historical cohort or registry, used when no concurrent control is feasible.