Encyclopaedia

Explore comprehensive, evidence-informed explanations of key health economics concepts, including their development, application and relationships to other concepts. Published entries are validated through human expert review.

Concepts, entries and ontology terms

A concept page is a published entry on the wiki. Some concepts also have a full encyclopaedia article. The Health Economics Ontology (HEO) holds every concept, including dictionary terms without an article, so it is larger than the list of published pages. The knowledge graph shows how concepts relate to each other.

Spearman Correlation

Spearman correlation is a rank-based measure from -1 to +1 of how consistently two variables, such as disease severity and costs, rise or fall together.

Evidence SynthesisExpert Verified3 related concepts

Specificity

Specificity is the share of people without the target condition whom a diagnostic test correctly calls negative, setting how many false positives arise.

Evidence SynthesisExpert Verified10 related concepts

Spline Model

A spline model is a regression model that joins polynomial pieces at knots to fit a flexible curve, such as hospital cost by age or survival over time.

Economic ModellingExpert Verified3 related concepts

Standard Costing

Standard costing sets the expected cost of a health service in advance from standard quantities and prices, then compares actual costs with this benchmark.

Economic EvaluationExpert Verified2 related concepts

Standard Deviation

Standard deviation is a measure of how widely patient costs, outcomes or other values spread around their mean, in the same units as the data.

Evidence SynthesisExpert Verified6 related concepts

Standard Error

The standard error (SE) is the standard deviation of an estimate's sampling distribution, showing how precisely a mean cost or treatment effect is known.

Evidence SynthesisExpert Verified5 related concepts

Standard Gamble

The standard gamble (SG) values a health state for QALYs as the chance of full health, against death, that makes a gamble as good as the state for sure.

Economic EvaluationExpert Verified4 related concepts

Standard Normal

The standard normal distribution is a normal distribution with mean 0 and standard deviation 1, used in health economics to read z values as probabilities.

Evidence SynthesisExpert Verified2 related concepts

Standardised Mean Difference

The standardised mean difference (SMD) is a mean difference divided by a standard deviation, used to pool continuous outcomes measured on different scales.

Evidence SynthesisExpert Verified5 related concepts

Standardised Mortality Ratio

The standardised mortality ratio (SMR) is observed deaths divided by deaths expected at reference rates for a group's age mix, used to gauge excess deaths.

NHS ProductivityExpert Verified4 related concepts

Standardised Residual

A standardised residual is a regression residual divided by its estimated standard deviation, used to flag outlying patients in cost and outcome models.

Evidence SynthesisExpert Verified3 related concepts

Standardised Response Mean

The standardised response mean (SRM) is a responsiveness index for health outcome measures, the mean change divided by the standard deviation of change.

Economic EvaluationExpert Verified2 related concepts

State Occupancy

State occupancy is the expected time a modelled cohort spends in a health state, found by adding the share of the cohort in that state across model cycles.

Economic ModellingExpert Verified3 related concepts

State Reward

A cost, utility, health outcome, or other consequence accrued while a modelled person occupies a specified state for a defined amount of time.

Economic ModellingExpert Verified2 related concepts

State Space Model

A state space model is a time series model where hidden states, such as disease severity or service demand, evolve over time and are measured with error.

Economic ModellingExpert Verified1 related concept

State Transition Model

A state transition model is a decision model in which a cohort or simulated patients move between health states over time to estimate costs and QALYs.

Economic ModellingExpert Verified2 related concepts

Statistical Power

Statistical power is the probability a trial gives a significant result when a true effect of set size exists, used to size clinical and economic trials.

Evidence SynthesisExpert Verified3 related concepts

Statistical Process Control

Statistical process control (SPC) is a set of statistical methods for monitoring health service data over time to tell routine variation from real change.

NHS ProductivityExpert Verified4 related concepts

Statistical Significance

Statistical significance is a threshold-based conclusion that an observed result is sufficiently incompatible with a prespecified null hypothesis under a stated statistical model to meet the chosen significance level.

Evidence SynthesisExpert Verified1 related concept

Steady State

A steady state in a Markov model is the stationary distribution of a cohort across health states, unchanged from cycle to cycle under fixed transitions.

PharmacoeconomicsExpert Verified1 related concept