Encyclopaedia

Explore comprehensive, evidence-informed explanations of key health economics concepts, including their development, application and relationships to other concepts. Published entries are validated through human expert review.

Concepts, entries and ontology terms

A concept page is a published entry on the wiki. Some concepts also have a full encyclopaedia article. The Health Economics Ontology (HEO) holds every concept, including dictionary terms without an article, so it is larger than the list of published pages. The knowledge graph shows how concepts relate to each other.

Prospective Risk Adjustment

Prospective risk adjustment adjusts health plan or provider payments for a coming period using diagnoses and demographics from an earlier base period.

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Provider Payment

Provider payment is how health purchasers pay doctors and hospitals, for example by budget, salary, fee-for-service, per diem, case (DRG) or capitation.

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Pseudo-Random Number

A pseudo-random number is a value produced by a deterministic algorithm whose sequence is designed to exhibit specified statistical properties of random draws.

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QALY Calculation Method

The process of computing quality-adjusted life years by multiplying time spent in a health state by its utility value, then summing across states.

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QALY Shortfall

QALY shortfall is the expected QALY gap between a matched general population and patients on current care, which NICE reads as absolute or proportional.

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Quality of Care

Quality of care is the extent to which health services raise the chance of desired health outcomes and follow current professional knowledge.

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Quality of Evidence

Quality of evidence is a judgement, rated high to very low in GRADE, of how far a review, guideline or HTA can trust that an effect estimate is correct.

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Quality Score

A quality score is a single number summing checklist items to rate a study's methodological quality, now discouraged in favour of risk of bias judgements.

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Quality-Adjusted Life Year (QALY)

A quality-adjusted life year (QALY) combines length and quality of life in one measure: a year in full health counts as one QALY and death counts as zero.

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Quality-Adjusted Time Without Symptoms

Quality-adjusted time without symptoms (Q-TWiST) sums cancer survival time with toxicity, free of symptoms and after relapse, each weighted for quality.

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Quasi-Experimental Design

A quasi-experimental design estimates the causal effect of a health policy or treatment without randomisation, using a comparison group or period instead.

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Queuing Model

A queuing model is a mathematical representation of how arrivals, service times, capacity, and service rules generate waiting, congestion, and throughput in a service system.

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Random Effects Model

A random effects model is a meta-analysis model that lets true treatment effects differ between trials and estimates their mean and between-study variance.

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Random Number Generation

Random number generation supplies the uncertain draws used in probabilistic sensitivity analysis, microsimulation, discrete-event simulation, bootstrap procedures, and other stochastic analyses.

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Random Parameter Model

A random parameter model, or mixed logit, is a discrete choice model in which preference weights vary across people, estimated as a mean and a spread.

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Random Sampling

Random sampling selects members of a population by chance, giving each a known, non-zero probability of selection, so sample estimates can be generalised.

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Randomised Controlled Trial

A randomised controlled trial (RCT) is a study that assigns people to an intervention or comparator by chance, HTA's preferred source of relative effects.

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Randomization

Randomisation assigns participants to treatments by chance, balancing known and unknown prognostic factors on average so effects used in HTA are unbiased.

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Rate-to-Probability Conversion

Rate-to-probability conversion turns an event rate, such as deaths per person-year, into the probability of the event within one cycle of a Markov model.

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Ratio Scale

Ratio scale is a level of measurement with equal intervals and a true zero, such as cost or survival time, so a claim of twice the cost is meaningful.

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