Encyclopaedia

Explore comprehensive, evidence-informed explanations of key health economics concepts, including their development, application and relationships to other concepts. Published entries are validated through human expert review.

521540 of 682 concepts

Response Surface Methodology

Statistical techniques for modelling and optimising the relationship between several inputs and an output by fitting a smooth surface to limited results.

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Restricted Cubic Spline

A flexible function of piecewise cubic segments joined smoothly at knots, constrained to behave linearly beyond the outermost knots.

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Restricted Cubic Splines

A collection of piecewise cubic functions joined at knots and constrained to extend linearly beyond the data range, used to model non-linear hazard shapes.

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Restricted Mean Survival Time

A survival summary measure calculated as the area under the survival curve up to a specified time point, an alternative to the hazard ratio.

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Return on Assets

A financial ratio calculated as net income divided by total assets, showing how efficiently an organisation uses its assets to generate profit.

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Return on Equity

A financial ratio calculated as net income divided by owner equity, showing the return generated on capital invested by an organisation's owners.

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Return on Investment

A measure of an investment's profitability, calculated as the net gain from the investment divided by its cost.

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Reynolds-Smolensky

An index measuring the redistributive effect of a tax or transfer system, calculated as the difference between pre-tax and post-tax income Gini coefficients.

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Right Censoring

The most common form of censoring, occurring when follow-up ends or a patient is lost before the event of interest has occurred.

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Robust Optimisation

An optimisation approach seeking a solution that performs well across a range of possible uncertain parameter values, rather than one best-guess scenario.

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Robust Standard Error

An estimate of a regression coefficient's statistical uncertainty that remains valid even when standard modelling assumptions, such as constant error variance, are violated.

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ROC Curve

A graph depicting the trade-off between a test's true positive rate and false positive rate across a full range of decision thresholds.

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Rollback

An alternative term for folding back, the process of solving a decision tree by working backward from final outcomes to the initial node.

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Root Mean Square Error

A measure of average prediction error, the square root of the average squared difference between predicted and observed values, in the outcome's units.

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Rounding Error

The difference introduced when a numerical value is rounded to fit a limited number of digits.

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Royston-Parmar Model

A class of flexible parametric survival models using restricted cubic splines to represent a transformed survival or hazard function while remaining fully parametric.

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Sample Size Calculation

The process of determining the number of participants a study needs to have an adequate chance of detecting a specified treatment effect.

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Sandwich Estimator

A method calculating an estimator's variance that remains valid even when standard model assumptions are violated, forming the basis of robust standard errors.

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Scale Efficiency

A measure of whether a provider is operating at its optimal size, distinct from whether it uses its current scale of inputs efficiently.

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Scaled Schoenfeld

A diagnostic technique testing the proportional hazards assumption by scaling Schoenfeld residuals by their variance to improve test power.

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