Cost-of-Illness Study — Functions & Formulae

Economic-burden estimation function

c(inputs,boundary) = Economic Burden

Maps attributable resource use losses population counts and valuation assumptions to the economic burden of a disease injury or risk factor.

Bottom-up population burden
```
B_bottom = c_bar_attr * N_aff
```
Scales the mean attributable cost per affected person to the defined affected population.
Top-down attributable burden
```
B_top = X_agg * AF
```
Applies a disease-attributable fraction to compatible aggregate expenditure.
Total economic burden by category
```
B_total = sum_(k=1)^K B_k
```
Adds the mutually exclusive cost categories included under the stated study perspective and boundary.