Dictionary
The Dictionary provides concise definitions of health economics terms, arranged alphabetically for quick reference. Use it to understand unfamiliar terminology or confirm the meaning of a specific term.
A
- Accelerated Approval
- A regulatory pathway allowing a drug for a serious unmet need to gain approval based on a surrogate endpoint, with confirmatory trials required afterward.
C
- Confirmatory Trial
- A trial conducted after accelerated approval based on a surrogate endpoint, verifying the anticipated clinical benefit using a more definitive, patient-relevant outcome.
P
- Post-Marketing Requirement
- A study regulators formally mandate a manufacturer conduct after approval, often as a condition of accelerated approval granted on a surrogate endpoint.
S
- Surrogate Endpoint
- A trial outcome used as a substitute for a direct clinical benefit measure, such as survival, based on its expected predictive relationship to that outcome.