DALY rate per 100,000 population for a cause

Divides the DALYs from a cause by the population in which they arise and scales the result to 100,000 people, the form in which GBD 2021 reports all-age and age-specific rates. A rate removes the effect of population size but not of age structure; age-standardised rates weight age-specific rates by a standard population, as in HE-FM-INEQ-001.

Signature

DALY_rate = DALY / Pop * 100000
Inputs
InputsDefinitionUnit
DALYDALYs from the cause in the population and yearDALYs
PopPopulation of the same location, sex, age group and yearpeople
Output
DALY_rateDALYs from the cause per 100,000 peopleDALYs per 100,000 population

Function

Disability-adjusted life years for a cause or a scenario from years of life lost and years lived with disability

Maps the deaths and the non-fatal health loss from a cause, or in one scenario of an economic evaluation, to disability-adjusted life years (DALYs) by adding the years of life lost (YLL) to the years lived with disability (YLD), each calculated by its own formula. YLLs are deaths times a standard loss function of the age at death (HE-FN-YLL-001, HE-FM-YLL-001, with the discounted form HE-FM-YLL-003 and the age-group total HE-CF-YLL-001), and YLDs are prevalent cases times a disability weight (HE-FM-DWT-001) or incident cases times the weight and the duration (HE-FN-YLD-001, HE-FM-YLD-001, discounted in HE-FM-YLD-002). This package adds the sum itself, the DALYs of a cohort in one scenario, DALYs averted and cost per DALY averted between two scenarios, the continuously discounted cohort form and the DALY rate per 100,000 population. DALYs averted by a change in disability weights alone, with mortality unchanged, are HE-FM-DWT-005, and the general incremental ratio is HE-FM-ICER-001. Notation follows the Disability-Adjusted Life Year article.

Try this function

Implementations

  • Excel

    DALY rate per 100,000 from named cells

    With DALYCount and Population named, the cell returns DALYs per 100,000 population, held in DALYRate.

    =DALYCount/Population*100000

Assumptions

  • DALY count and population for the same place, group and year

    The DALYs and the population refer to the same location, sex, age group and year. An all-age rate depends on the age structure, so comparisons between places or over time use age-specific or age-standardised rates.

Worked examples

  • Illustrative district DALY rate per 100,000

    If the article's illustrative 1,440 DALYs arose in a district of 250,000 people, an illustrative population, the rate would be 576 DALYs per 100,000 population.

    DALY = 1440; Pop = 250000; DALY_rate = 576
  • DALY rate in a population of exactly 100,000 as a limiting case

    When the population is 100,000 the rate equals the DALY count, a check that the scaling is applied once.

    DALY = 1440; Pop = 100000; DALY_rate = 1440

Common errors

  • Reading a rise in DALY counts as worsening population health

    GBD 2021 found that global DALYs rose to 2.88 billion in 2021 against 2.63 billion in 2010, while the age-standardised DALY rate fell by 14.2% between 2010 and 2019, so much of the rise came from population growth and ageing. The age-standardised rate then rose again in 2020 and 2021 during the COVID-19 pandemic. Counts and all-age rates are read alongside the age-standardised rate.

Sources

  • GBD 2021 counts and rates per 100,000 population

    GBD 2021 Diseases and Injuries Collaborators. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021, a systematic analysis for the Global Burden of Disease Study 2021. The Lancet. 2024;403(10440) 2133-2161 (full text read). Methods, where metrics are estimated as counts, all-age and age-specific rates per 100 000 population and age-standardised rates per 100 000 using the GBD standard population. Findings, with global DALYs of 2.63 billion in 2010 and 2.88 billion in 2021 and a 14.2% fall in the global age-standardised all-cause DALY rate between 2010 and 2019, reversed during the first 2 years of the COVID-19 pandemic.

    View source →

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